Pineal® Notte Retard | Laborest


Pineal® Notte Retard

Sleep is defined as a state of rest that is opposite to being awake. Physiological sleep is characterised by REM and NON-REM stages. Deep sleep is experienced during the REM stages, when you enter the oneiric stage. Sleep problems are very common; if persistent, they can negatively affect daily activities, altering psycho-physical wellbeing. Stress and anxiety are common factors that may accompany these problems also affecting the quality of sleep.

Product details

Pharmaceutical form

24 gluten and lactose-free tablets  Gluten free  Lactose-free


Food supplement containing Melatonin, Griffonia, Hops, Valerian and Black Pepper.

Melatonin is a crucial hormone during physiological sleep: it reduces the time required to drift off* and is useful also to reduce jet lag symptoms in the case of long trips**.
It is a hormone secreted by the pineal gland and its main effects include the stabilisation of REM (Rapid Eyes Movement) stages.
*The beneficial effect is obtained by taking 1 mg of melatonin shortly before bedtime.
**The beneficial effect is obtained by taking, shortly before bedtime, at least 0.5 mg of melatonin on the first day of the trip and for the first few days after arrival.

Griffonia is a plant whose seeds contain a high concentration of a special amino acid, Tryptophan, which is the fundamental substratum for the production of various compounds in the body.
Tryptophan is an essential amino acid, i.e. it needs to be integrated in the diet since our body cannot produce it endogenously. It is the sole precursor of serotonin and melatonin. Serotonin is a neurotransmitter with several effects, including that of elevating mood.

Griffonia maintains a normal mood by favouring mental wellbeing and, together with Valerian and Hops, it favours the process of falling asleep and promotes sleep.
Valerian is a flowering plant that belongs to the Valerianaceae family; the molecules that can be obtained from this plant include the esters of valerenic acids, some flavonoids and diterpenic compounds known as iridinoids.
Valerian and Hops promote sleep and relaxation.

Take 1 tablet of PINEAL® NOTTE RETARD  in the evening, shortly before bedtime.
To solve the problem of waking at night, take PINEAL® NOTTE RETARD for the time and with the frequency that is best suited to your needs.
PINEAL® NOTTE RETARD can be taken also by people who are gluten or lactose intolerant or sensitive.

No cases of addiction have been reported in connection with product usage.

The PINEAL® NOTTE line includes PINEAL® NOTTE FAST, drops that promote sleep, PINEAL® NOTTE D, with Melatosoma® and Vitamin D and the practical formulation of PINEAL® NOTTE SPRAY.

Nutrition facts

Average quantity of characterising components
Components Per tablet
Valerian d.e. 500 mg
Hops d.e. 170 mg
Black pepper d.e.
of which piperine
5.3 mg
5.04 mg
Griffonia d.e.
25 mg
24.75 mg
Melatonin 1 mg